Duan, R, Tong, J, Lin, L, Levine, L, Sammel, M, Stoddard, J, Li, T, Schmid, C, Chu, H, and Chen, Y. PALM: Patient-centered Treatment Ranking via Large-scale Multivariate Network Meta-analysis, The Annals of Applied Statistics (June 2022). (selected as Best of AoAS by the editor-in-chief)
Hattle, M, Burke, D, Trikalinos, T, Schmid, C, Chen, Y, Jackson, D, Riley, R. Multivariate meta-analysis of multiple outcomes: characteristics and predictors of borrowing of strength from Cochrane reviews, Systematic Reviews journal 11.1 (2022): 1-12.
Liu, YL, Ying, GS, Graham, Q, Zhou, XH and Chen, Y. Extending Hui-Walter framework to correlated outcomes with application to diagnosis tests of an eye disease among premature infants, Statistics in Medicine 2022 Feb 10;41(3):433-448
Rosenberger, K, Duan, R, Chen, Y, and Lin, L, Predictive P-score for treatment ranking in Bayesian network meta-analysis, BMC Medical Research Methodology 21.1 (2021): 1-10.
Zhou, T, Zhou, J, Hodges, J, Lin, L, Chen, Y, Cole, S, and Chu, H, Estimating the Complier Average Causal Effect in a Meta-analysis of Randomized Clinical Trials with Binary Outcomes Accounting for Noncompliance: A Generalized Linear Latent and Mixed Model Approach, American Journal of Epidemiology (2021) 191(1):220-229
Xiao, M, Chen, Y, Cole, S, MacLehose RF, Richardson, DB, Chu, H. Is OR “portable” in meta-analysis? Time to consider bivariate generalized linear mixed model, Journal of Clinical Epidemiology (2021) S0895-4356(21)00243-2.
Xiao, M, Chu, H, Cole, S, Chen, Y, MacLehose, R, Richardson, DB and Greenland, S. Odds ratios are far from “portable”—A call to use realistic models for effect variation in meta-analysis, Journal of Clinical Epidemiology (2021) S0895-4356(21)00242-0.
Lian, X, Zhang, J, Hodges, J, Chen, Y and Chu, H. Accounting for Post-randomization Variables in Meta-analysis: A Joint Meta-Regression Approach, Biometrics (August, 2021)
Rott, K, Shi, A, Lin, L, Hodges, J, Siegel, L, Chen, Y and Chu, H. Bayesian meta-analysis using SAS PROC BGLIMM, Research Synthesis Methods 12(6):692-700
ML Delle Monache, K Chi, Chen, Y, P Goatin, K Han, JM Qiu, B Piccoli. A Three-Phase Fundamental Diagram from Three-Dimensional Traffic Data, (March, 2021) Axioms 10 (1). This paper was selected as an issue cover.
Mishra, A, Dey, D, Chen, Y, and Chen, K: Generalized Co-sparse Factor Regression. Computational Statistics and Data Analysis 157, May 2021 Notes: doi: 10.1016/j.csda.2020.107127. Epub ahead of print.
Marks-Anglin, A, Luo, C, Piao, J, Gibbons, M, Schmid, C, Ning, J and Chen, Y: EMBRACE: an EM-based Bias Reduction Approach through Copas-Model Estimation for Quantifying the evidence of selective publishing in network meta-analysis. Biometrics 2021 Feb 9.
Duan, R, Ning, Y and Chen, Y: Heterogeneity-aware communication efficient distributed statistical inference Biometrika 23 Mar 2021,
Lian, X, Zhang, J, Hodges, J, Chen, Y and Chu, H. Accounting for Post-randomization Variables in Meta-analysis: A Joint Meta-Regression Approach, Biometrics 2021 Sep 29
Huang, J, Cai, Y, Du, J., Li, R., Ellenberg, S.S., Hennessy, S., Tao, C., and Chen, Y . (Sep., 2020) Monitoring vaccine safety by studying temporal variation of adverse events using vaccine adverse event reporting system. The Annals of Applied Statistics 15(1): 252-269.
Marks-Anglin, A and Chen, Y (August, 2020) A Historical Review of Publication Bias. Research Synthesis Methods Volume 11, Issue 6, November 2020, Pages 725, 742
Marks-Anglin, A and Chen, Y (July, 2020), Small-study effects: current practice and challenges for future research, Statistics and Its Interface,Volume 13 (2020), Number 4, Pages 475 – 484
Huang, J, Ning, Y, Reid, N and Chen, Y (Jan., 2020), On specification tests for composite likelihood inference, Biometrika, Volume 107, Issue 4, December 2020, Pages 907–917.
Hong, C, Salanti, G, Morton, S, Riley, R, Chu, H, Kimmel, S, and Chen, Y (September 2019) Testing small study effects in multivariate meta-analysis, Biometrics. 2020 Dec; 76(4): 1240–1250..
Bai, R, Moran, G, Antonelli, J, Chen, Y and Boland, M. (May, 2020) Spike-and-Slab Group Lassos for Grouped Regression and Sparse Generalized Additive Models. Journal of the American Statistical Association.
Chen, Y, Liang, K-Y, Tong, P, Beaty, T, Barnes, K. and Kao, L. (May, 2020) A pseudolikelihood approach for assessing genetic association in case-control studies with unmeasured population structure, Statistical Methods in Medical Research, 2020 Nov;29(11):3153-3165.
Ning, J, Cai, C, Chen, Y, Huang, X and Wang, MC. (Jan., 2020) Semiparametric Modelling and Estimation of Covariate Adjusted Dependence between Bivariate Recurrent Events, Biometrics. Volume 76, Issue 4, December 2020, Pages 1229-1239
Duan, R, Ning, Y, Wang, S, Lindsay, B, Carroll, R, and Chen, Y (Dec., 2019) A fast score test for generalized mixture models, Biometrics 21 December 2019 (This paper won 2018 ENAR Distinguished Student Paper Award)
Hong, C, Duan, R, Zeng, L, Hubbard, R, Lumley, T, Riley, R, Chu, H, Kimmel, S and Chen, Y (2019+) Galaxy plot: a new visualization tool of bivariate metaanalysis studies, American Journal of Epidemiology, Volume 189, Issue 8, August 2020, Pages 861–869.
Wang, L, Chai, X, Chen, Y, and Chen, J (August 2019) Novel Two-Phase Sampling Designs for Studying Binary Outcomes, Biometrics 2020 Mar;76(1):210-223.
Liu, YL, Huang, J, Urbanowicz, R, Chen, K, Manduchi, E, Greene, C, Scheet, P, Moore, JH., and Chen, Y. (August 2019) Embracing study heterogeneity for finding genetic interactions in large‐scale research consortia. Genetic Epidemiology, Volume 44, Issue 1, January 2020, Pages 52-66
Duan, R, Cao, M, Ning, Y, Zhu, M, Zhang, B, McDermott, A, Chu, H, Zhou, X, Moore, J, Ibrahim, J, Scharfstein, D, Chen, Y (July, 2019), Global identifiability of latent class models with applications to diagnostic test accuracy studies: a Grobner basis approach, Biometrics, Volume 76, Issue 1, March 2020, Pages 98-108
Cai, Y, Huang, J, Ning, J, Lee, ML, Rosner, B and Chen, Y (September 2019), Two-sample test for correlated data under outcome-dependent sampling with an application to self-reported weight loss data, Statistics in Medicine, Volume 38, Issue 25, 10 November 2019, Pages 4999-5009
Shen, W, Liu, S, Chen, Y and Ning, J. (December 2018) Regression analysis of longitudinal data with outcome-dependent sampling and informative censoring . Scandinavian Journal of Statistics, Volume 46, Issue 3, September 2019, Pages 831-847
Hubbard, R, Huang, J, Harton, J, Oganisian, A, Choi, G, Utidjian, L, Eneli, I, Bailey, L, Chen, Y (September 2018) A Bayesian latent class approach for EHR-based phenotyping, Statistics in Medicine, Volume 38, Issue 1, 15 January 2019, Pages 74-87
Hong, C, Riley, R and Chen, Y (March, 2018) An improved method for bivariate meta-analysis when within study correlations are unknown, Research Synthesis Methods, 9(1):73–88.
Zhang, J, Ko, CW, Nie, L, Chen, Y and Tiwari, R. (Feb, 2018) Bayesian hierarchical methods for meta-analysis combining randomized controlled and single-arm studies, Statistical Methods in Medical Research, 28 issue: 5, page(s): 12931310.5
Chen, Y, Huang, J, Ning, Y, Liang, K-Y and Lindsay, B. (March, 2018) A conditional test for composite likelihood with boundary constraints. Biometrika 105 (1), 225-232.
Huang, J, Ning, Y, Liang, K-Y and Chen, Y (2018), Composite likelihood inference under boundary conditions, Statistica Sinica, Vol. 30, No. 2 (2020), pp. 1005-1025.
Ma, X, Lian, X, Chu, H, Ibrahim, J, and Chen, Y (Jan., 2018) A Bayesian hierarchical model for network meta-analysis of diagnostic tests, Biostatistics, 2018 Jan 1;19(1):87-102
Hong, C, Ning, Y, Wei, P, Cao, Y and Chen, Y. (2017) A semiparametric model for vQTL mapping, Biometrics 73(2): 571-581.
Hong, C, Ning, Y, Wang, S, Wu, H, Carroll, RJ and Chen, Y. (2017) PLEMT: A novel pseudolikelihood based EM test for homogeneity in generalized exponential tilt mixture models, Journal of the American Statistical Association 112 (50).(This paper won 2015 JSM Biometrics section Byar Awards)
Chen, Y, Ning, J, Ning, Y, Liang, K-Y and Bandeen-Roche, K. (2017) On pseudolikelihood inference for semiparametric models with boundary problems . Biometrika, 104 (1): 165–179.
Huang, J, Liu, YL, Vitale, S, Penning, T, Whitehead, A, Vachani, A, Clapper, M, Muscat, J, Lazarus, P, Scheet, P, Moore, JH and Chen, Y (Dec., 2017), On meta- and mega-analyses for gene environment interactions, Genetic Epidemiology 41(8): 876–886.
Piao, J, Liu, YL, Chen, Y and Ning, J. (July, 2017) Copas-like selection model to correct publication bias in systematic review of diagnostic test studies, Statistical Methods in Medical Research. 18(3):495–504.
Wang, L, Chen, Y and Zhu, H (2017) Implementing Optimal Allocation in Clinical Trials with Multiple Endpoints, Journal of Statistical Planning and Inference 182, 88-99.
Ning, J, Chen, Y, and Piao, J (July, 2017) Maximum likelihood estimation and EM algorithm of Copas selection model for publication bias correction. Biostatistics, 18(3): 495–504.
Liu, Y, DeSantis, S and Chen, Y (2017) Bayesian mixed treatment comparisons meta-analysis for correlated outcomes subject to reporting bias, Journal of the Royal Statistical Society: Series C, 67(1): 127–144.
Li, X, Chen, Y, and Li, R (Feb., 2017) A frailty model for recurrent events during alternating restraint and non-restraint time periods, Statistics in Medicine, 20 February 2017.
Chen, Y, Liu, Y, Chu, H, Lee, M and Schmid, C (2017) A simple and robust method for multivariate meta-analysis of diagnostic test accuracy, Statistics in Medicine, 36(1):105-121.
Sun, H, Wang, Y, Chen, Y, Li, Y and Wang, S. (June, 2017)pETM: a penalized Exponential Tilt Model for analysis of correlated high-dimensional DNA methylation data. Bioinformatics, 33(12):1765-1772.
Liu, Y, Chen, Y and Scheet, P (2016), A meta-analytic framework for detection of genetic interactions, Genetic Epidemiology, 40 (7), 534-543.
Chen, Y, Hong, C, Ning, Y and Su, X. (Jan., 2016) Meta-analysis of studies with bivariate binary outcomes: a marginal beta-binomial model approach, Statistics in Medicine, 35(1):21–40.
Chen, Y Cai, Y, Hong, C, and Jackson, D. (2016) Inference for correlated effect sizes using multiple univariate meta-analyses, Statistics in Medicine, 35(9): 1405-1422.
Ning, J, Chen, Y, Cai, C, Huang, X and Wang, MC. (2015) On the Dependence Structure of Bivariate Recurrent Event Processes: Inference and Estimation, Biometrika 102(2): 345-358.
Liu, Y, Chen, Y and Chu H. (2015) A unification of models for meta-analysis of diagnostic accuracy studies without a gold standard, Biometrics, 71(2):538–47.
Chen, Y, Ning, J and Cai, C. (2015) Regression analysis of longitudinal data with irregular and informative observation times, Biostatistics, 16(4): 727-739.
Ning, Y and Chen, Y. (2015) A class of pseudolikelihood ratio tests for homogeneity in exponential tilt mixture models, Scandinavian Journal of Statistics 42 (2), 504-517.
Chen, Y, Hong, C and Riley, R. (2015) An alternative pseudolikelihood method for multivariate random effects meta-analysis, Statistics in Medicine 34 (3): 361-380.
Chen, Y, Liu, Y, Ning, J, Cormier J and Chu H. (2015) A hybrid model for combining case?control and cohort studies in systematic reviews of diagnostic tests, Journal of the Royal Statistical Society: Series C, 64(3): 469-489.
Chen, Y, Liu, Y, Ning, J, Nie, L, Zhu, H and Chu H. (Dec., 2014) A composite likelihood method for bivariate analysis of sensitivity and specificity in diagnostic reviews, Statistical Methods in Medical Research. 26(2).
Chen, Y, Chu, H, Luo, S, Nie L and Chen S. (2014) Bayesian analysis on meta-analysis of case control studies accounting for within study correlation, Statistical Methods in Medical Research.. 26(2).7
Chen, Y, Luo, S, Chu, H, Su, X and Nie, L. (2014) An Empirical Bayes Method for Multivariate Meta-analysis with Application in Clinical Trials, Communications in Statistics-Theory and Methods, 43(16), 3536-3551.
Ma, X, Chen, Y, Cole, S and Chu, H. (May, 2014) A hybrid Bayesian hierarchical model combining cohort and case control studies for meta-analysis of diagnostic tests: accounting for partial verification bias, Statistical Methods in Medical Research. 25(6).
Luo, S, Chen, Y, Su, X and Chu, H. (2014) mmeta: An R package for multivariate meta-analysis. Journal of Statistical Software, 56 (11).
Chen, Y, Luo, S, Chu, H and Wei, P. (2013) Bayesian inference on risk differences: an application to multivariate meta-analysis of adverse events in clinical trials, Statistics in Biopharmaceutical Research, 5 (2): 142-155.
Nie, L, Soon, G, Qi, K, Chen, Y and Chu, HT. (2013) A note on partial covariate adjustment and design considerations in noninferiority trials when patient level data are not available, Journal of Biopharmaceutical Statistics, 23 (5), 1042-1053.
Chen, Y, Ning, Y, Hong, C and Wang, S. (2013) Semiparametric tests for identifying differentially methylated loci with case-control designs using Illumina arrays, Genetic Epidemiology, 38 (1), 42{50.
Tong P, Chen, Y, Su X and Coombes K (2013) SIBER: Systematic Identification of Bimodally Expressed Genes Using RNAseq Data. Bioinformatics, 29 (5), 605-613.
Chu, H, Nie, L, Chen, Y, Huang, Y and Sun, W. (2012) Bivariate random effects models for meta-analysis of comparative studies with binary outcomes: methods for the absolute risk difference and relative risk, Statistical Methods in Medical Research, 21 (6): 621-633.
Nie, L, Chen, Y and Chu, H. (2011) Asymptotic Variances of Maximum Likelihood Estimator for the Correlation Coecient from a BVN Distribution with One Variable Subject to Censoring , Journal of Statistical Planning and Inference, 141 (1), 392-401.
Chen, Y and Liang, KY. (2010) On the asymptotic behaviour of the pseudolike ratio test statistic with boundary problemslihood, Biometrika, 97 (3), 603-620.
Li, W, Tong, J, Anjum, M, Mohammed, N, Chen, Y and Jiang, X. (Oct 2022) Federated Learning Algorithms for Generalized Mixed-effects Model (GLMM) on Horizon-tally Partitioned Data from Distributed Sources. BMC medical informatics and decision making 22 (1).
Hu, H, Liu, XK, Zheng, Y, He, X, Hart, Jaime, James, P, Laden, F, Chen, Y and Bian, J. (Jun 2022) Methodological Challenges in Spatial and Contextual Exposome-Health Studies. Critical Reviews in Environmental Science and Technology, 1-20.
Liu, XK, Duan, R, Luo, C, Ogdie, A, Moore, J, Kranzler, H, Bian, J, and Chen, Y. (Jun 2022) ADAP: multisite learning with high-dimensional heterogeneous data via A Distributed Algorithm for Penalized regression. Scientific Reports, , 12(1), 11073.
Luo, C., Chen, K, Doshi, R, Rickles, N, Chen, Y, Schwartz, H, and Aseltine, R. (Jun 2022). The association of prescription opioid use with suicide attempts: An analysis of statewide medical claims data. Plos One, 17(6), p.e0269809.
Luo, C., Du, J, Butler, A, Cuker, A, Lautenbach, E, Asch, D, Poland, G, Tao, C and Chen, Y. (Jun 2022). Comparability of clinical trials and spontaneous reporting data regarding COVID-19 vaccine safety. Scientific Reports, 12(1), p.10946.
Luo, C., Islam, M.N., Sheils, N.E., Buresh, J., Schuemie, M.J., Doshi, J.A., Werner, R.M., Asch, D.A. and Chen, Y. (2022). dPQL: a lossless distributed algorithm for generalized linear mixed model with application to privacy-preserving hospital profiling. Journal of the American Medical Informatics Association, 29.8 (2022): 1366-1371.
Tong, J, Luo, C, Islam, M, Sheils, N, Buresh, J, Edmondson, M, Merkel, P, Lautenbach, E, Duan, R and Chen, Y. An efficient distributed algorithm with application to COVID-19 data from heterogeneous clinical sites. NPJ Digital Medicine, 5, 76 (2022).
Edmondson, M.J., Luo, C., Islam, M.N., Sheils, N.E., Buresh, J., Chen, Z., Bian, J. and Chen, Y. Distributed Quasi-Poisson Regression Algorithm for Modeling Multi-Site Count Outcomes in Distributed Data Networks. Journal of Biomedical Informatics, (2022): 104097.
Luo, CL, Duan, R, Naj, A, Kranzler, H, Bian, J and Chen, Y. A One-shot Distributed Algorithm for Cox model with Heterogeneous Multi-center Data. Scientific reports, 12(1), p.6627.
Luo, C, Marks-Anglin, A, Duan, R, Lin, L, Hong, C, Chu, H and Chen, Y. Accounting for small-study effects using a bivariate trim and fill meta-analysis procedure. Statistics in Medicine (accepted).
Luo, C., Islam, M.N., Sheils, N.E., Buresh, J., Reps, J., Schuemie, M.J., Ryan, P.B., Edmondson, M., Duan, R., Tong, J., Marks-Anglin, A., Bian, J., Chen, Z., Duarte-Salles, T., Fernandez-Bertolin, S., Falconer, T., Kim, C., Park, R., Pfohl, S, Shah, N., Williams, A., Xu, H., Zhou, Y., Lautenbach, E., Doshi, J., Werner, R., Asch, D., and Chen, Y. (February 2022). DLMM as a lossless one-shot algorithm for collaborative multi-site distributed linear mixed models. Nature Communications, 1678 (13). This is an OHDSI study with 120,609 COVID-19 patients from 11 international sites across three continents.
Huang, Y, Luo, C, Jiang, Y, Du, J, Tao, C, Chen, Y, and Hao, Y. A Bayesian Network to Predict the Risk of Post Inuenza Vaccination Guillain-Barre Syndrome: A Development and Validation Study. JMIR Public Health & Surveillance, 8.3 (2022): e25658.
Chen, A, Luo, C, Chen, Y, Shinohara, R, Shou, H., and Alzheimer’s Disease Neuroimaging Initiative. Privacy-preserving harmonization via distributed ComBat. NeuroImage, Volume 248, March 2022, 118822
Che, S., Kong, Z., Peng, H., Sun, L., Leow, A., Chen, Y. and He, L., (2022). Federated Multi-View Learning for Private Medical Data Integration and Analysis. ACM Transactions on Intelligent Systems and Technology (TIST), 13(4), pp.1-23.
Liu, XK, Chubak, J, Hubbard, R. and Chen, Y. SAT: a Surrogate Assisted Two-wave case boosting sampling method, with application to EHR-based association studies. Journal of the American Medical Informatics Association, Journal of the American, Medical Informatics Association. 2022 Apr 13;29(5):918-27.
Schuemie, M.J., Chen, Y, Madigan, D, Suchard, M.A., Combining Cox Regressions Across a Heterogeneous Distributed Research Network Facing Small and Zero Counts. Statistical Methods in Medical Research. November 2021.
Yin, Z, Tong, J, Chen, Y, Hubbard, R, and Tang, CY. A Cost-effective Chart Review Sampling Design to Account for Phenotyping Error in EHR data. Journal of the American Medical Informatics Association, 2021 Dec 28;29(1):52-61.
Holmes, J, Beinlich, J, Boland, MR, Bowles, RH, Chen, Y, Cook, TS, Demiris, G, Draugelis, M, Fluharty, L, Gabriel, P.E., Grundmeier, R, Hanson, W, Herman, D.S., Himes, B.E., Hubbard, R.A., Kahn C.E., Kim, D., Koppel, R, Long, Q, Mirkovic, N, Morris, J.S., Mowery, D, Ritchie, M, Urbanowicz, R, and Moore, J.H., Why Is the Electronic Health Record So Challenging for Research and Clinical Care? Methods of Information in Medicine, 2021; 60(01/02); 032-048.
Edmondson, M, Luo, C, Duan, R, Maltenfort, M, Chen, Z, Locke, K, Shults, J, Bian, J, Ryan, P, Forrest, C and Chen, Y. An Efficient and Accurate Distributed Learning Algorithm for Modeling Multi-Site Zero-Inflated Count Outcomes. Scientific Reports. 2021 Oct 4;11(1):19647
Li, Q, Zhang, H, Chen, Z, Guo, Y, George, TJ, Chen, Y, Wang, F, Bian, J. Validate Real-World Data-based Endpoint Measures of Cancer Treatment Outcomes. AMIA Annu Symp Proc 2021.
Hubbard, R, Xu, J, Siegel, R, Chen, Y, Eneli, I: Studying pediatric health outcomes with electronic health records using Bayesian clustering and trajectory analysis. Journal of Biomedical Informatics Dec 2020 Notes: doi: 10.1016/j.jbi.2020.103654. Online ahead of print.
Du, J, Xiang, Y, Sankaranarayanapillai, M, Zhang, M, Wang, J, Si, Y, Pham, H, Xu, H, Chen, Y, Tao, C: Extracting post-marketing adverse events from safety reports in the Vaccine Adverse Event Reporting System (VAERS) using deep learning. Journal of the American Medical Informatics Association 2021, 2021 Jul 14;28(7):1393-1400.
Luo, C, Jiang, Y, Du, J, Tong, J, Huang, J, Lo Re, V, Ellenberg, S, Poland, G, Tao, C and Chen, Y: Prediction of post-vaccination Guillain-Barre syndrome using data from a passive surveillance system. Pharmacoepidemiology and Drug Safety 2021, Volume 30, Issue 5, May 2021, Pages 602-609
Li, R, Duan, R, Zhang, X, Lumley, T, Pendergrass, S, Bauer, C, Hakonarson, H, Carrell, D, Smoller, J, Wei, W, Carroll, R, Edwards, D, Wiesner, G, Sleiman, P, Denny, J, Mosley, J, Ritchie, M, Chen, Y and Moore, J Lossless integration of multiple electronic health records for identifying pleiotropy using summary statistics Nature Communications 12(1): 168, Jan 2021 Notes: doi: 10.1038/s41467-020-20211-2
Zuo X, Chen Y, Ohno-Machado L, Xu H: How do we share data in COVID-19 research? A systematic review of COVID-19 datasets in PubMed Central Articles. Briefings in Bioinformatics 2020 Notes: https://doi.org/10.1093/bib/bbaa331.
Gonzalez-Hernandez, G, Lu, Z, Leaman, R, Weissenbacher, D, Boland, M., Chen, Y, Du, J, Fluck, J, Greene, C, Holmes, J, Kashyap, A, Nielsen, R, Ouyang, Z, Schaaf, S, Taroni, J, Tao, C, Zhang, Y, Liu, H. (Oct, 2019) PSB 2019 Workshop on Text Mining and Visualization for Precision Medicine, Pacific Symposium on Biocomputing 2019, pp. 449-454 (2018)
Du, J, Luo, C, Shegog, R, Bian, J, Cunningham, R, Boom, J, Poland, G, Chen, Y, Tao, C. (August, 2020) Use of deep learning to analyze Twitter discussions about HPV vaccine beliefs and attitudes, JAMA Network Open 2020;3(11):e2022025
Tong, J, Chen, Z, Duan, R, Lo-Ciganic, W, Lyu, T, Tao, C, Merkel, P, Kranzler, H, Bian, J, Chen, Y. (July 2020) Identifying Clinical Risk Factors of Opioid Use Disorder using a Distributed Algorithm to Combine Real-World Data from a Large Clinical Data Research Network. AMIA Annu Symp Proc. 2021 Jan 25;2020:1220-1229. eCollection 2020.
Duan, R., Chen Z., Tong, J., Luo, C., Lyu, T., Tao, C., Maraganore, D., Bian, J. and Chen, Y. (July 2020) Leverage real-world longitudinal data in large clinical research networks for Alzheimers disease and related dementia. AMIA Annu Symp Proc. 2021 Jan 25;2020:393-401. eCollection 2020.
Duan, R., Zhang, X.,Du, J., Huang, J., Tao, C and Chen, Y .(July, 2020). On the evidence consistency of pharmacovigilance outcomes between Food and Drug Administration Adverse Event Reporting System and electronic medical record data for acute mania patients. Health Informatics Journal 2020 Jun; 26(2):753-764.
Raisaro, JL, Marino, F, Troncoso-Pastoriza, J, Bernstam, E.V., Chen, Y, Gottlieb, A, Kim, M, Klann, J, Klersy, C, Malin, B, Mean, M, Prasser, F, Scudeller, L, Wong, S, Frenkel-Morgenstern, M, Xu, H, Jiang, X, Hubaux, JP. (July 2020) SCOR: A secure international informatics infrastructure to investigate COVID-19. Journal of the American Medical Informatics Association, Volume 27, Issue 11, November 2020, Pages 1721–1726.
Li, R, Tong, J, Duan, R, Chen, Y and Moore, J (June, 2020), Evaluation of phenotyping errors on polygenic risk score predictions, International Conference on Bioinformatics Models, Methods and Algorithms, ISBN 978-989-758-398-8; ISSN 2184-4305, pages 123-130.
Duan, R, Luo, C, Schuemie, M.J., Tong, J, Liang, J., Chang, H., Boland, M.R., Bian, J., Xu, H., Holmes, J., Forrest, C., Morton, S., Berlin, J.A., Moore, J.H., Mahoney, K.B. and Chen, Y. (June, 2020) Learning from local to global — an efficient distributed algorithm for modeling time to event data, Journal of the American Medical Informatics Association Volume 27, Issue 7, July 2020, Pages 1028–1036.
Moore, J, Barnett, I, Boland, M, Chen, Y, Demiris, G, Gonzalez-Hernandez, G, Herman, D, Himes, B, Hubbard, R, Kim, D, Morris, J, Mowery, D, Ritchie, M, Shen, L, Urbanowicz, R, and Holmes, J. (May, 2020) Ideas for how informaticians can get involved with COVID-19 research. BioData Mining 13, Article number: 3 (2020)
Li, R, Chen, Y, Ritchie, M and Moore, J. (March, 2020) Electronic health records and polygenic risk scores for predicting disease risk. Nature Reviews Genetics 21, pages493–502 (2020)
Hubbard, R, Tong, J, Duan, R and Chen, Y. (Dec, 2019) Reducing Bias Due to Outcome Misclassification for Epidemiologic Studies Using EHR-derived Probabilistic Phenotypes. Epidemiology, 31(4), pp.542-550.
Tong, J, Duan, R, Li, R, Scheuemie, M, Moore, J and Chen, Y. (Oct, 2019) Robust-ODAL: Learning from heterogeneous health systems without sharing patient-level data. In Pacific Symposium on Biocomputing (Vol. 25, pp. 695-706).
Duan, R, Boland, MB, Liu, ZX, Liu, Y, Chang, H, Xu, H, Chu, H, Schmid, C, Forrest, C, Holmes, J, Schuemie, M, Berlin, J.A. and Chen, Y. (Oct, 2019) Learning from Electronic Health Records Across Multiple Sites: A Communication-efficient and Privacy-preserving Distributed Algorithm. Journal of the American Medical Informatics Association, Volume 27, Issue 3, March 2020, Pages 376–385.
Tong, J, Huang, J, Wang, X, Moore, J, Hubbard, R and Chen, Y. (Sep. 2019) An augmented estimation procedure for EHR-based association studies accounting for differential misclassification. Journal of the American Medical Informatics Association, Volume 27, Issue 2, February 2020, Pages 244–253.
Jia, Y, Zhu, C, Du, J, Xiang, Y, Chen, Y, Wang, W and Tao, C. (Aug. 2019) Investigating Safety Profiles of Human Papillomavirus Vaccine Across Group Differences using VAERS Data and MedDRA, PeerJ 7:e7490 https://doi.org/10.7717/peerj.7490.
Maltenfort, M, Chen, Y and Forrest, C. (Aug. 2019) Prediction of 30-day pediatric unplanned hospitalizations using the Johns Hopkins Adjusted Clinical Groups Risk Adjustment, Plos One 2019 Aug 15;14(8):e0221233.
Huang, J, Chen, Y, Landis, R and Mahoney, K. (July, 2019) Patient portal: how does it change our health behaviors and outcomes? – a retrospective, observational cohort study at Penn Medicine, Journal of Medical Internet Research [co-first author] 2019;21(10):e13146
Huang, J, Zhang, X, Tong, J, Du, J, Duan, R, Liu, Y, Moore, J, Tao, C and Chen, Y. (July, 2019) Comparing drug safety of Hepatitis C therapies using post-market data. BMC Medical Informatics and Decision Making 19(4), pp1-12.
Li, R, Duan, R, Kember, R, Regeneron Genetic Center, Rader, D, Damrauer, S, Moore, J and Chen, Y. (July, 2019) A regression framework to uncover pleiotropy in large-scale electronic health record data. Journal of the American Medical Informatics Association Volume 26, Issue 10, October 2019, Pages 1083–1090
Du, J, Cunningham, RM, Xiang, Y, Li, F, Jia, Y, Boom, JA, Myneni, S, Bian, J, Luo, C, Chen, Y and Tao, C. (April 2019) Leveraging deep learning to understand health beliefs about the Human Papillomavirus Vaccine from social media. Nature Partner Journal (NPJ) Digital Medicine. 2, Article number: 27 (2019).
Li, R, Chen, Y and Moore, J (April 2019). Integration of genetic and clinical information to improve imputation of data missing from electronic health records. Journal of the American Medical Informatics Association, Volume 26, Issue 10, October 2019, Pages 1056–1063.
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Singh, J, Kallan, M, Chen, Y, Parks, M, Ibrahim, S. (accepted in Aug, 2019) Association of Race/Ethnicity with Hospital discharge disposition after Elective Total Knee Arthroplasty, JAMA Network Open 2019 Oct; 2(10): e1914259.
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Ashana, D, Umscheid, C, Stephens-Shields, A, Kohn, R, Madden, V, Harhay, M, Chen, Y, Kerlin, M. (Aug. 2019) Determining the association between end-of-life care resources and patient outcomes in Pennsylvania intensive care units, Critical Care Medicine.
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Umscheid, C, Jonathan, W, Matthew, G, Jenna G, Tessa, C, Liu, YL, Chen, Y, and Jennifer, M. (June 2019) National Survey of Hospitalists Experiences with Incidental Pulmonary Nodules. Journal of Hospital Medicine 14(6):353-356
Leas, B, Kahwati, L, Liu, Y, Chen, Y, D’Anci, K, and Umscheid, C, (2018) Using Qualitative Comparative Analysis (QCA) to Assess Interventions for Improving Asthma Care, Academy Health Research Meeting.
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