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Dr. Yong Chen Presents Causal AI framework for Drug Development at the ASA STATBOLIC 2026 conference

Dr. Yong Chen Presents Causal AI framework for Drug Development at the ASA STATBOLIC 2026 conference

Dr. Yong Chen presented the XYZ framework, a simple “three variable” way to think about causal AI in drug development where X is the treatment, Y is the outcome, and Z is the population. By holding any two pieces fixed and solving for the third,

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Bingyu Zhang and Yiwen Lu Discuss Long COVID and BMI Research in The Daily Pennsylvanian

Bingyu Zhang and Yiwen Lu Discuss Long COVID and BMI Research in The Daily Pennsylvanian

PennCIL Lab PhD candidates Bingyu Zhang and Yiwen Lu were recently interviewed by The Daily Pennsylvanian about a RECOVER EHR study published in Journal of Infection linking body mass index to Long COVID symptoms in youth.

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Significant Cost Savings of Telemedicine, our study reported by U.S. News and others

Significant Cost Savings of Telemedicine, our study reported by U.S. News and others

Our lab’s recent work on telemedicine is attracting significant attention and has been covered by major outlets, including U.S. News & World Report, HealthDay and Penn Medicine News. Led by PhD candidate Bingyu Zhang and Dr.

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Invited Talk Featured on AI-Powered Rare Disease Diagnostics

Invited Talk Featured on AI-Powered Rare Disease Diagnostics

Dr. Yong Chen shared insights on AI-powered rare disease diagnostics at the International Genomic Medicine Symposium. (Nov 2025)

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New NIH Funding Featured on Alzheimer’s Research Initiative

New NIH Funding Featured on Alzheimer’s Research Initiative

Dr. Yong Chen is named an MPI on a new $27.2 million NIH initiative to unify Alzheimer’s research data across 10 leading institutions. (Oct 2025)

https://ldi.upenn.edu/our-work/research-updates/27-2-million-national-effort-launches-to-unify-alzheimers-research-data/

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New Funding Featured by PennLDI and Politico!

Dr. Yong Chen’s $8 million grant from the National Institute of Mental Health to develop an AI-driven framework that could transform how we detect and diagnose mental health conditions was recently featured by Penn LDI and Politico.

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Recent Study on COVID Vaccination Attracting Worldwide Interest!

Check out this article by Penn Medicine News that highlights our study recently published in Lancet eClinicalMedicine on COVID vaccination! This study showed that BNT162b2 vaccination significantly reduced the risk of long COVID in kids and teens during both Delta and Omicron waves—mainly by preventing infection in the first place.

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Recent Studies on Long-COVID Gaining Attention!

Four recent PennCIL studies, featured in a recent Penn Medicine News release, are gaining national attention for shedding light on the long-term health effects of COVID-19 in children—and the protective role of vaccination.

📚 Read more about the science and its impact:

Penn Medicine

ReachMD

Philly Voice

Scienmag

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Recent study featured by Healio!

Check out this article by Healio that highlights our study recently published in JAMA Network Open!

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Recent study featured by TechTarget!

Check out this article by TechTarget that highlights our study recently published in Cell Patterns!

 

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Recent study featured by Penn Medicine News!

Our manuscript published in Cell Patterns this November on post-acute COVID-19 healthcare demands was featured by Penn Medicine News! Check out the news release here.

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Alumni Featured by Penn DBEI!

Former PhD student, Dr. Rui Duan, was recently featured in a Penn Department of Biostatistics, Epidemiology and Informatics Alumni spotlight. Check it out here!

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Dr. Yong Chen Presenting Short Course at DISS2025

Dr. Yong Chen will be one of three speakers presenting a short course entitled, “AI/ML applications through the lenses of statisticians from regulatory agency, industry, and academia,” at the Duke Industry Statistics Symposium which will take place April 9-11,

Presentations

Recent PhD graduate Huan He has been appointed Assistant Professor of Statistics and Data Science at Auburn University.

Recent PhD graduate Huan He has been appointed Assistant Professor of Statistics and Data Science at Auburn University. Congratulations Huan!

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Recent PhD graduate Qiong Wu has been appointed Assistant Professor of Biostatistics at the University of Pittsburgh.

Recent PhD graduate Qiong Wu has been appointed Assistant Professor of Biostatistics at the University of Pittsburgh. Congratulations Qiong!

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Recent PhD graduate Jessie Tong has been appointed Assistant Professor of Biostatistics at Johns Hopkins University.

Recent PhD graduate Jessie Tong has been appointed Assistant Professor of Biostatistics at Johns Hopkins University. Congratulations Jessie!

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Dazheng Zhang Presents Lightning Talk at OHDSI 2024 Global Symposium

PhD student Dazheng Zhang presented a lightning talk during the OHDSI 2024 Global Symposium. See his talk here!

Presentations

Jessie Tong Presents Lightning Talk at the OHDSI 2024 Global Symposium

Recent PhD graduate Jessie Tong presented a lightning talk during the OHDSI 2024 Global Symposium. See her talk here!

Presentations
Our New Annals of Internal Medicine paper Efficacy of BNT162b2 Bivalent Vaccine Against Delta and Omicron Variants in Pediatrics is online

Our New Annals of Internal Medicine paper Efficacy of BNT162b2 Bivalent Vaccine Against Delta and Omicron Variants in Pediatrics is online

Our new Annals of Internal Medicine paper, Efficacy of BNT162b2 Bivalent Vaccine Against Delta and Omicron Variants in Pediatrics, is online on January 9, 2024! Senior authors are Yong Chen, Christopher B.

News AnnalsofInternalMedicine COVID19Research PediatricVaccineStudy PublicHealth

Dr. Yong Chen was elected as a 2023 ACMI Fellow

Yong Chen, PhD, FASA, FAMIA, Professor of Biostatistics, and the Founding Director of the Computing, Inference, and Learning Lab at the University of Pennsylvania (PENNCIL) and the Center for Health Analytics and Synthesis of Evidence (CHASE) will be inducted,

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🎉 Congratulations to PhD student Jessie Tong on winning the Titan Award for methodological research at 2023 OHDSI Global Symposium

🎉 Congratulations to PhD student Jessie Tong on winning the Titan Award for methodological research at 2023 OHDSI Global Symposium

🎉 Congratulations to PhD student Jessie Tong on winning the Titan Award for methodological research at 2023 OHDSI Global Symposium! Also congratulations to all the other 2023 OHDSI award winners!

Award #OHDSI #Titan award
PhD student Bingyu Zhang presented during the lightning talk session at OHDSI 2023 Global Symposium

PhD student Bingyu Zhang presented during the lightning talk session at OHDSI 2023 Global Symposium

UPenn AMCS graduate student Bingyu Zhang shared her work on quantifying racial/ethnic differences in pediatric long COVID during the lightning talk session at 2023 OHDSI Global Symposium. Link to the video of the talk: https://youtu.be/VMjslT0k_HM?t=1260.

Presentations #OHDSI
PHD student Lu Li presented during the lightning talk session at OHDSI 2023 Global Symposium

PHD student Lu Li presented during the lightning talk session at OHDSI 2023 Global Symposium

UPenn AMCS graduate student Lu Li shared her work on synthesizing evidence for rare events: a novel zero-inflated bivariate model to integrate studies with double-zero outcomes during the lightning talk session at 2023 OHDSI Global Symposium.

Presentations #OHDSI

Postdoc Fellow Xiaokang Liu is joining University of Missouri Department of Statistics in August

Postdoc fellow Xiaokang Liu is joining Department of Statistics at University of Missouri as an Assistant Professor in August 2023. We wish Xiaokang the best in the next chapter of her career!

News job
Postdoc fellow Qiong Wu won a poster award at ICSA 2023

Postdoc fellow Qiong Wu won a poster award at ICSA 2023

Congratulate postdoc fellow Dr. Qiong Wu for winning a poster award at ICSA 2023!

Award award

PhD candidate Ken Locke is joining GSK in May

PhD candidate Ken Locke is joining GSK as a Principal Statistician in May 2023. Congratulations on the next chapter of your career!

News job
PhD student Ken Locke successfully defense his dissertation

PhD student Ken Locke successfully defense his dissertation

PhD student Ken Locke defended his thesis on “Preserving patient privacy in modeling multi-category outcomes across real-world data sources”. Congratulations on a successful thesis defense!

News presentation

Postdoc fellow Naimin Jing is joining Merck in January

Postdoc fellow Dr. Naimin Jing is joining Merck as a Senior Scientist in Jan 2023. Congratulations on the next chapter of your career!

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PENNCIL TEAM IS LEADING A NATIONAL MULTI-INSTITUTIONAL STUDY TO USE AI TO ADVANCE EARLY DETECTION OF RARE DISEASES.

We are excited to launch this 4-year study, co-led by Peter Merkel at Penn and Jiang Bian at the University of Florida, to take real-world data based evidence generation to its next level of informing clinical practice and decision-making.

News collaboration

Postdoctoral Research Fellow Position Available

We are recruiting postdocs! For more information, please see the link https://forms.stat.ufl.edu/statistics-jobs/entry/7815/

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PhD candidate Mac Edmondson is joining Merck in 2021

PhD candidate Mac Edmondson is joining Merck as a Senior Scientist in 2021. Congratulations on the next chapter of your career!

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PhD candidate Arielle Marks-Anglin is joining Mathematica in 2021

PhD candidate Arielle Marks-Anglin is joining Mathematica as a Human Service Researcher in 2021. Best wishes for the next chapter of your career!

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Welcome postdoc research fellow Dr. Xiaokang Liu to our PennCIL group!

Welcome postdoc research fellow Dr. Xiaokang Liu to our PennCIL group! Yuchen got her PhD from the Department of Statistics at University of Connecticut. Find out more about her research here.

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Welcome postdoc research fellow Dr. Yuchen Yang to our PennCIL group!

Welcome postdoc research fellow Dr. Yuchen Yang to our PennCIL group! Yuchen got her PhD from the Department of Biostatistics at Johns Hopkins Bloomberg School of Public Health. Find out more about her research here.

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PhD student Rui Duan Dissertation Defense will be Held at 2pm on April 8th 2020

PhD student Rui Duan will defend her thesis, entitled “EHR Data + X: Expanding the Reach of EHR Through Data Integration” via BlueJeans, on April 8th at 2 pm.

News presentation

PhD student Rui Duan is Joining Harvard University in August

PhD student Rui Duan is joining Harvard University as a tenure-track Assistant Professor of Biostatistics in August 2020. Congratulations!!!

News job

Dr. Yong Chen was named Fellow of the American Statistical Association

Yong Chen, Ph.D. has been named fellow of the American Statistical Association (ASA), the field’s largest and most prestigious professional organization in the United States.
 
Please check out the DBEI news.

Award

EHR and Polygenic Risk Score for Predicting Disease Risk

Check out our recently published Nature Review Genetics paper on “Electronic health records and polygenic risk scores for predicting disease risk” coauthored by Ruowang Li, Yong Chen,

News paper

Postdoc Fellow Dr. Ray is Joining The University of South Carolina

Postdoc Fellow Dr. Ray Bai, advised by Dr. Yong Chen and Dr. Mary Boland, is joining The University of South Carolina as a tenure-track Assistant Professor of Statistics in August 2020.

News job

Congratulate Arielle Marks-Anglin for winning the ICHPS Student Paper Travel Award

Congratulate Arielle Marks-Anglin, a third-year PhD student advised by Dr. Yong Chen, for winning the International Conference on Health Policy Statistics (ICHPS) Student Paper Travel Award for her work on quantifying evidence of selective publishing in network meta-analysis!

News award

Bias reduction with EHR validation data

Check out our recent published paper on “An augmented estimation procedure for EHR-based association studies accounting for differential misclassification”, coauthored by Jiayi Tong, Jing Huang, Jessica Chubak, Xuan Wang,

News paper

Dr. Jing Huang and Dr. Yong Chen are joining the Statistics in Epidemiology (SIE) program

Dr. Jing Huang and Dr. Yong Chen are joining the Statistics in Epidemiology (SIE) program for the Speed Mentoring Breakfast event on Monday Morning at 2019 JSM.

News conference

Postdoc fellow Dr. Lifang He is joining Lehigh University in November 2019

Postdoc fellow Dr. Lifang He is joining Lehigh University as an Assistant Professor of Computer Science starting on November 1st, 2019. Congratulations!!!

News job

Members in PennCIL are attending the 2019 Joint Statistical Meetings (JSM) in Denver, Colorado

Members in PennCIL are attending 2019 Joint Statistical Meetings (JSM) in Denver, Colorado, which is the largest gathering of statisticians held in North America.

Rui Duan will give a presentation on “A Fast Score Test for Generalized Mixture Models”;

News conference

Postdoc Fellow Dr. Yulun Liu is joining UT Southwestern Medical Center

Postdoc fellow Dr. Yulun Liu is joining UT Southwestern Medical Center as an Assistant Professor of Biostatistics. Congratulations!!!

News job

Postdoc Fellow Dr. Jing Huang is joining University of Pennsylvania

Postdoc fellow Dr. Jing Huang is joining University of Pennsylvania as an Assistant Professor of Biostatistics. Congratulations!!!

News job

Congratulate PhD student Rui Duan for winning Jiann-Ping Hsu Pharmaceutical and Regulatory Sciences Student Paper

Congratulate Rui Duan, a third-year PhD student advised by Dr. Yong Chen, for winning Jiann-Ping Hsu Pharmaceutical and Regulatory Sciences Student Paper Award for her work “A fast score test for generalized mixture models”! Congratulations!!!

News award

Congratulate Dr. Jing Huang and Dr. Ruowang Li for Winning DBEI & CCEB Research Day Best Biostatistics and Informatics Presentation Award

Congratulate postdoc fellow Dr. Jing Huang for winning the DBEI & CCEB Research Day Best Biostatistics Presentation Award, Penn Medicine, 2018 for her talk on bias reduction in EHR-related research! Congratulations!!!
Congratulate postdoc fellow Dr.
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Congratulate PhD student Rui Duan's paper for winning the Eastern North American Region (ENAR) Distinguished Paper Award

Congratulate Rui Duan, a third-year PhD student advised by Dr. Yong Chen, for winning the Eastern North American Region (ENAR) Distinguished Paper Award, 2018! Congratulations!!
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